Fig. 5
From: TRPM4 regulates hilar mossy cell loss in temporal lobe epilepsy
Epileptic WT but not Trpm4−/− mice have impaired spatial memory. A Timeline of the experiments. Mice underwent KA or saline (ctrl) injection. Ten days later, behavioral tests were performed to assess spatial and contextual memory. B OLM test schematic and timeline. Statistics showing discrimination index (C) and number of object visit (D) in WT and Trpm4−/− mice. n = 8 for WTctrl, 9 for WTKA, 9 for Trpm4−/−ctrl, and 8 for Trpm4−/−KA.E OLM test schematic and timeline. Statistics showing discrimination index (F) and number of object visit (G) in WT and Trpm4−/− mice. n = 5 for WTctrl, 5 for WTKA, 5 for Trpm4−/−ctrl, and 5 for Trpm4−/−KA. Data are presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001