Table 1 Genomic patterns expected for scenarios of mitotic recombination, stress-induced DNA breaks, and meiotic recombination and observed in the studied Candida hybrids, in terms of number of LOH events, LOH size, LOH accumulation with time, LOH correlation with chromosome size, and distribution in the chromosomes
From: Evolution of loss of heterozygosity patterns in hybrid genomes of Candida yeast pathogens
Mitotic recombination | Stress-induced DNA breaks | Meiotic recombination | Observation in Candida hybrids | |
|---|---|---|---|---|
Large number of blocks | No | Yes | Yes | Yes |
Enrichment in large blocks | Yes | Yes | No | No |
Linear accumulation with time | Yes | No | No | No |
Negative correlation between LOH block and chromosome size | No | No | Yes | Sometimes |
Enrichment in the telomers | No | Yes | Yes | Yes |