Skip to main content
Fig. 1 | BMC Biology

Fig. 1

From: Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathy

Fig. 1

Single-cell RNA-seq reveals major cell classes in the human tendon. A The overall workflow of our research program. B MRI photographs of typical normal (up) and lesioned tendon (down). C A photograph of a typical lesioned tendon under an arthroscope. D t-SNE visualization of all cell clusters in collected tendons. E, F t-SNE visualization of the donor origins in normal/diseased samples. G Heatmap of selected marker genes in each cell cluster. H The percentages of the identified cell classes in normal/diseased tendons. I Number of differentially expressed genes (DEGs) in each cell type of normal/diseased status. J Feature plots of expression distribution for selected cluster-specific genes. Brighter colors indicate higher expression levels

Back to article page