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Fig. 3 | BMC Biology

Fig. 3

From: Regulation of mouse exploratory behaviour by irradiance and cone-opponent signals

Fig. 3

S-cone opponent colour signals modulate light-induced masking. A Experimental setup for passive infrared (PIR) activity monitoring and paradigm for delivery of stimuli of varying spectral composition (See Additional file 1. Fig. S3 for spectra). B, F Example PIR activity records from two Opn1mwR (B) and Cnga3−/− (F) mice. C, G Mean ± SEM activity counts during dark at varying intensities of ‘spectra 1’ for Opn1mwR (C, n = 12) and Cnga3−/− (G, n = 12) mice. Data analysed by one-way RM ANOVA with Tukey’s post tests (C: F1.2,12.9 = 62.4, P < 0.001; G: F2.0,21.7 = 107.3, P < 0.001). D, H Mean ± SEM activity suppression across test stimuli for Opn1mwR (D, n = 12) and Cnga3−/− (H, n = 12) mice. Shaded region indicates mean ± SEM activity suppression for the reference stimulus (‘spectra 1’). Data analysed by one-way RM ANOVA with Sidak’s post-tests against reference spectra (D: F4.0,43.8 = 8.0, P < 0.001; H: F4.1,44.6 = 5.3, P = 0.001). E, I Mean ± SEM normalised activity for Opn1mwR (E, n = 12) and Cnga3.−/− (I, n = 12) mice across the 1.5-h light phase for spectra 1 + , 2, 3 and 4 and comparison to the reference spectra (spectra 1)

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