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Fig. 2 | BMC Biology

Fig. 2

From: A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche

Fig. 2

Depletion of Twist2 lineage cells impaired villus homeostasis. a Depletion of the Twist2 or Acta2 lineage, but not the Prrx1 or Nestin lineage, led to shortening of the GI tracts. Right panel: quantitation data of the intestine length. N = 4. See additional file: Fig. S3e for details. b H/E, Ki67, goblet, lysozyme, and GFP staining of normal and Twist2 cell-depleted mouse intestinal villi. Also, see Fig. S3g for control. Bar: 50 μm. Bottom panels: quantitation data. **P < 0.01 and ***P < 0.001. ns: not significant. N = 5. Lgr5-GFP: Lgr5-EGFP-IRES-CreERT2

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