Fig. 2From: Diminished activation of excitatory neurons in the prelimbic cortex leads to impaired working memory capacity in miceThe activation of PrL neurons was associated with WMC. a,b Representative images show the FOS+ neurons in the PrL and IL of each group of mice. c Representative image show the PrL and IL. d The number of FOS+ neurons in the PrL (Two-way ANOVA, interaction: p > 0.05, task: p < 0.0001, genotype: p < 0.05; post hoc Tukey’s tests, *p < 0.05, ****p < 0.0001). n = 12 slices from four mice per group. e Relationship between the number of FOS+ neurons in the PrL and WMC in the task group mice (Linear regression, *p < 0.05). n = 8. f The number of FOS+ neurons in the IL (Two-way ANOVA, all p > 0.05; post hoc Tukey’s tests, all p > 0.05). n = 12 slices from four mice per group. g Relationship between the number of FOS+ neurons in the IL and WMC of in the task group mice (Linear regression, p > 0.05). n = 8. Data are presented as the mean ± SEMBack to article page