Fig. 4
From: Prefoldin 2 contributes to mitochondrial morphology and function
Loss of PFD2 leads to changes in proteins abundance involved in protein homeostasis. A, B Wildtype and Δpfd2 cells were grown at 25 °C (A) and shifted to 37 °C for 4 h (B). Volcano plots showing proteins with significantly increased (blue circles) and decreased (red circles) protein abundance in Δpfd2 versus wildtype cells. Adj. P-value of < 0.05 (FDR = 0.05) and fold change of 1.3 was considered as statistical significant change. Non-significant proteins are shown in gray circles. C Gene ontology enrichment of proteins with significantly downregulated (upper panel) or upregulated (lower panel) protein abundance in Δpfd2 cells compared with wildtype grown at 25 °C. Values next to the right side of the bars indicate the numbers of proteins with the certain GO term. WT, wild type