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Fig. 5 | BMC Biology

Fig. 5

From: Expression profiles of the autism-related SHANK proteins in the human brain

Fig. 5

Conserved SHANK2 isoform expression in human and rodent brain regions. SHANK2 isoform expression in human (a), mouse (c), and rat (e) brain lysates. b SHANK2 isoforms in motor neuron (MN) lysates in comparison to a mouse CTX sample (here: 7 µg). d Quantification of total SHANK2E, SHANK2A, and SHANK2 in mouse brain regions, n = 3. Levels were normalized to the CB, horizontal lines indicate the mean. f The brain regions available from all species were blotted next to each other. Dashed lines indicate different exposure times for the left and right half of the membrane. g Summary of isoform expression in human (orange) and mouse (gray), shading represents expression strength. kDa = kilodalton, N/D = not defined, h = human, m = mouse, r = rat. The uncropped blots are shown in Additional file 9

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