Fig. 6

Intracerebroventricular injection of FL1 recovers ASD and anxiety-like behaviors of FL mice. A Quantification of the time animals spend having seizures. B Percentage of time in a 1h session that animals spend grooming. C Elevated plus maze test to determine the percentage of time spent in the open arms. D–F Light and dark test measuring the latency to enter the bright field (D), number of crosses to light (E), and percentage of time in bright field (F). G Contextual fear conditioning test to measure long-term memory formation at 24 h. N = 10 animals per condition were analyzed. Bars represent mean ± SEM; ***p < 0.001. One-way ANOVA was used to determine significance compared to wild-type condition