A systematic scientometric review of paternal inheritance of acquired metabolic traits

Table 3 Quantitative description of the manuscripts included in the systematic review (updated August 2023)

			Exposure							Vehicle	Outcome
Study design	Pub	Multi	Tox	Diet	Exe	Psy	sncRNA	KO/KI	Other	Sperm	Pheno	Behav	Metab	Microb	Endoc	sncRNA	lncRNA	Methyl	Histone
Human, Prospective	17	4	3	3	0	1	0	0	9	0	10	2	2	0	1	0	0	2	0
Human, Retrospective (historical)	8	1	3	2	0	0	0	0	3	0	7	0	3	0	1	0	0	0	0
Animal, Ancestral exposure, Descriptive (associative)	105	9	45	29	8	15	1	4	10	30	71	40	77	5	20	13	1	39	8
Animal, Ancestral exposure, Mechanistic	15	2	3	3	0	2	2	6	5	12	4	2	6	0	0	5	0	10	4
Animal, Gamete/embryo exposure, Descriptive (associative)	130	75	82	33	5	10	0	0	10	33	90	29	102	2	31	10	0	49	15
Animal, Gamete/embryo exposure, Mechanistic	20	6	2	4	0	2	7	4	4	10	12	5	11	0	0	3	0	8	6

Abbreviations: Pu publications, Multi Multigenerational studies (i.e., studies on exposures repeated over multiple generations), tox toxicant, Exe exercise, psy psychological/mental challenge, sncRNA manipulation with exogenous small RNA, KO/KI gene knock-out/knock-in, Pheno phenotype, Behav behavior, Metab metabolic phenotype, Microb gut microbiota, Endoc Endocrine balance, sncRNA small non-coding RNA, lncRNA long non-coding RNA, Methyl methylation

ISSN: 1741-7007