Fig. 1
From: Circulating cell-free DNA fragmentation is a stepwise and conserved process linked to apoptosis
DNA fragmentation is tightly linked with cell apoptosis. A Electrophoresis analysis of the typical apoptotic DNA ladder extracted from HL60 cells cultured in different conditions including serum starvation (SS) for 72 h, high density (HD) for 72 h, room temperature (RT) for 14 h, and camptothecin (CPT) treatment for 5 h. Marker: 100 bp, 250 bp, 500 bp, 750 bp, 1000 bp, 2000 bp. 1.0% agarose gel. B Electrophoresis analysis of the apoptotic DNA ladder extracted from HL60 cells cultured at RT for 18 h, 24 h, 36 h, and 48 h. C, D May-Grunwald Giemsa (MGG) cell morphology and TdT-mediated dUTP nick-end labeling (TUNEL) cell apoptosis analyses of control and HL60 cells cultured at RT for 18 h, 24 h, 36 h, and 48 h