Fig. 3
From: DNA polymerases in precise and predictable CRISPR/Cas9-mediated chromosomal rearrangements
Mechanistic differences for 1bp and 2–100bp deletions. Significant increases of the frequency of 1bp deletions (A, D, G, J, M) and decreases of the frequency of 2–100bp deletions (B, E, H, K, N and C, F, I, L, O) upon PolQ knockdown at the MAZ (A–C), MeCP2 (D–F), PARP1 (G–I), PRDM5 (J–L), and YY1 (M–O) loci (see Additional file 5: Table S3, n = 3 replicates, mean ± SEM). The data for PolD or PolK knockdown were not conclusive