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Fig. 1 | BMC Biology

Fig. 1

From: Leveraging the predictive power of 3D organoids in dogs to develop new treatments for man and man’s best friend

Fig. 1

Immunofluorescent staining of canine bladder cancer organoids showing similar expression profiles of dog and human bladder cancer. A PAX8 (marker commonly identified in human bladder cancer, in red); DAPI (cell nuclei, blue) overlay. B CK5 (cytokeratin marker often positive in human bladder cancer, in red; UPK1 (uroplakin 1 marker, identifies bladder cancer origin, in green; DAPI (cell nuclei, in blue) overlay. C P53 (tumor suppressor gene marker often positive in human bladder cancer, in red; DAPI (cell nuclei, in blue) overlay. Scalebars: 100 μm (A), 500 μm (B and C)

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