Fig. 2

Performance of DisoFLAG in predicting disorder and disordered functions using different feature representations. a AUC value comparisons of DisoFLAG using different features, including protein language model-based features (ProtT5 and ProtBERT) and classic protein feature representations by position-specific scoring matrix (PSSM) and amino acid one-hot encodings (One-hot). The performance of DisoFLAG in predicting disorder (b) and disordered functions (c–e) for sequences with different multiple sequence alignment (MSA) depths