Fig. 7

Summary of common and specific responses to desiccation and ionizing radiation. Common damages known to be induced by desiccation and ionizing radiation: membrane damages, ROS production leading to phospholipid peroxidation and de-esterification, protein damages (oxidation, disulfide bridge, denaturation, aggregation, misfolding), and DNA damages (double-strand break: DSB, single-strand break: SSB, chemical modifications). The major molecular responses observed in Adineta vaga post-rehydration (with or without radiation; in yellow) and post-radiation (in blue), or common to both (in pink). Genes coding for some antioxidants, HSPs, high mobility proteins, and one CCAAT enhancer were found to be constitutively highly expressed (in green) in all conditions including controls. We found genes coding for HSPs, major vault proteins (MVP), glucose repressive proteins (Grg1), aldehyde dehydrogenase, regulation factors such as CCAAT enhancer, histone variants genes involved in protein modifications like ubiquitination, in proteolysis, DNA repair (mostly NHEJ and BER pathways) and RNA repair, being OE in the common response to rehydration and irradiation. Specific to rehydration, we found OE genes coding for Late Embryogenesis Abundant proteins (LEA), heat shock proteins (HSPs), tubulin, glucose repressive proteins (Grg1), and more antioxidants. Radiation increases the number of OE genes coding for histone variants, RNA/DNA repair proteins, and MVPs