Fig. 8.From: The accumulation of modular serine protease mediated by a novel circRNA sponging miRNA increases Aedes aegypti immunity to fungusSchematic diagram of the novel-circ-930, miRNA-novel-53, and ModSP response to fungal infection. Left panel: physiological condition, miRNA-novel-53 with silencing complex inhibits the translation of ModSP by targeting its CDS region in the cytoplasm, which maintains the basic expression level of ModSP. Right panel: infectious condition, the reduction of miRNA-novel-53 sponged by novel-circ-930 leads to an elimination of the repression of ModSP mRNA. The protein level of ModSP then significantly increases to defend fungal infectionBack to article page