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Fig. 8. | BMC Biology

Fig. 8.

From: The accumulation of modular serine protease mediated by a novel circRNA sponging miRNA increases Aedes aegypti immunity to fungus

Fig. 8.

Schematic diagram of the novel-circ-930, miRNA-novel-53, and ModSP response to fungal infection. Left panel: physiological condition, miRNA-novel-53 with silencing complex inhibits the translation of ModSP by targeting its CDS region in the cytoplasm, which maintains the basic expression level of ModSP. Right panel: infectious condition, the reduction of miRNA-novel-53 sponged by novel-circ-930 leads to an elimination of the repression of ModSP mRNA. The protein level of ModSP then significantly increases to defend fungal infection

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