Fig. 4

Odorant receptor and odorant binding protein genes in Culex quinquefasciatus and their evolution in mosquitoes. A Comparison of odorant receptors (ORs) and odorant-binding proteins (OBPs) annotated in current and previous assemblies. “Merged” genes represent cases where a single gene in the new assembly corresponds to 2–3 putative haplotypes present in the old assembly. “New” genes include ORs that were annotated on extrachromosomal contigs of J3 but have now been placed on a chromosome (newly assembled), ORs that were present in J3 but not annotated (newly annotated), and ORs that were completely absent from J3 (newly present). Unplaced genes were present in J3 but are absent from the new assembly. B Number of ORs and OBPs present in the genomes of three mosquito species. Dark and light sections of each bar correspond to full-length genes and fragments, respectively. C Inferred evolutionary relationships among ORs from three mosquito species. Maximum likelihood tree inferred using PhyML v3.0.0 based on translated protein sequences. The names of ORs with a single conserved ortholog in each species are labeled. See Additional file 1: Fig. S5 for tree with all gene names. Numbers of OBPs and ORs in An. gambiae and Ae. aegypti taken from [21, 33, 59]