Fig. 4

Performance of brain cellular deconvolution models is not equitable across all brain datasets. Violin plots of the distribution of the error, measured by the CETYGO score, associated with estimating the cellular proportions from DNA methylation data generated from brain tissues. A Adult prefrontal cortex samples grouped by experimental batch (n = 377). B Adult brain samples grouped by brain region (n = 851). C Prenatal and childhood cortical samples grouped by developmental stage (n = 167). CETYGO scores taken from reference panel 1 with an ANOVA to select cell-specific sites