Fig. 3
Long-range correlation of gene expression and frequency of chromatin-accessible regions. A Low correlation of SAR frequency and average gene expression of SEG sets in a 80-kB TSS vicinity of SEGs (R = 0.08, p-value >0.05). B SARs and SEGs are not correlated across 400 kB, R < 0.15, p-value>0.05 over 400 kB. C Correlation of DARs frequency (Methods) and average gene expression of corresponding DEG gene sets in a 80-kB TSS vicinity of DEG’s TSS, R > 0.7, p  <0.05. D Zones of ‘influence’ (positive correlation of accessibility and gene expression) for DARs - DEGs, R > 0.7, p < 0.05. E Correlation of H3K27ac frequency (Methods) and average gene expression of corresponding DEG gene sets in a 80-kB TSS vicinity of DEGs TSS, R > 0.7, p < 0.05. F Zones of ‘influence’ (positive correlation of accessibility and gene expression) for H3K27ac - DEGs, R > 0.7, p < 0.05 for maximal correlation around 100 kB