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20th Anniversary Collection

A collection of Comment articles from past authors, reviewers and Editorial Board Members sharing their perspective on the past and future of their fields

Call for Papers - Thematic Collections

Our Collections welcoming submissions: Stem cells and cancer, Plants and their pathogens, Epigenetic modifications and regulation, Mechanobiology, Regulation of gene expression through RNA

To increase our engagement with the Editorial Board and community at large, we are recruiting new Editorial Board Members to join us in a collaborative editorial initiative. Read more here. 

If you are interested, please complete the form here. Please note that we are unable to respond to all applications personally but will be in contact if your expertise meets the needs of the journal.

Deep learning to detect senescent stem cells

A morphology-based method, Cascade R-CNN, offers large scale identification of senescence in mesenchymal stem cells

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Mechanical stimulation of blood vessel growth

VEGFR-2 can be mechanically activated through strain in tumor microenvironment models, which may contribute to failure of anti-angiogenic cancer therapies

Follicular fluid components promote oocyte maturation

C3a-peptide from follicular fluid promotes F-actin aggregation and spindle migration in meiotic division of oocytes

Featured Review

Epistasis and evolution: recent advances and an outlook for prediction

Milo S. Johnson, Gautam Reddy & Michael M. Desai

Published on: 24 May 2023


Articles

Review
X-ray computed tomography in life sciences
Shelley D. Rawson et al.
Published 27 February 2020

Comment
The merger that made us
Buzz Baum and David Baum
Published 24 June 2020

Review
Protein assembly systems in natural and synthetic biology
Giulio Chiesa et al.
Published: 26 March 2020

Comment
Improving the usability and comprehensiveness of microbial databases​​​​​​​
Caitlin Loeffler et al.
Published: 07 April 2020


Focus: Plant Pathogens

The broad use of the Pm8 resistance gene in wheat resulted in hypermutation of the AvrPm8 gene in the powdery mildew pathogen
Lukas Kunz et al.
Published in BMC Biology 8 February 2023

Combined pangenomics and transcriptomics reveals core and redundant virulence processes in a rapidly evolving fungal plant pathogen
Hongxin Chen et al.
Published in BMC Biology 6 February 2023

The extrachromosomal circular DNAs of the rice blast pathogen Magnaporthe oryzae contain a wide variety of LTR retrotransposons, genes, and effectors
Pierre M. Joubert & Ksenia V. Krasileva
Published in BMC Biology 23 November 2022

The Venturia inaequalis effector repertoire is dominated by expanded families with predicted structural similarity, but unrelated sequence, to avirulence proteins from other plant-pathogenic fungi
Mercedes Rocafort et al.
Published in BMC Biology 3 November 2022

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Evolutionary Genomics

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Physics of Living Matter
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In the Light of Evolution
 

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Nature Communitites: Behind the Paper

We are now collaborating with Nature Communities, allowing authors to share experiences designing the study and collecting data by writing their own blog-style post on the paper. 

Read the latest Behind the Paper articles here:

Cones, sticks and croissants: Early cephalopod evolution
Alexander Pohle
Published Apr 14 2022

Tentacular team up: Deep partnerships between sea anemones and bacteria
Shana Goffredi
Published Jan 18 2021

Who's a Bonehead? Novel Insights into Evolutionary History from Reptilian Skull Roof Structure
Roy Ebel
Published Nov 30 2020

Digging into the past of olive trees
Toni Gabaldón
Published Oct 26 2020

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