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In situ genetic targeting of intestinal epithelium stem cells

Rudolph and co describe a novel technique for robust and reproducible in vivo targeting of stem cells in the unperturbed intestinal epithelium of mice.

Testicular pathogenesis of COVID-19

SARS-CoV-2 shows high tropism to the testis of severe patients, infecting macrophages and spermatogonia, and remaining infective after a long period.

To increase our engagement with the Editorial Board and community at large, we are recruiting new Editorial Board Members to join us in a collaborative editorial initiative. Read more here. 

If you are interested, please complete the form here. Please note that we are unable to respond to all applications personally but will be in contact if your expertise meets the needs of the journal.

Pericentromeric transcription of human Satellite 1A

Evidence for pericentromeric transcription of human Satellite 1A DNA suggests that deeper understanding of the role of HSat1A transcripts in different biological contexts is needed.

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Apply to become an Editorial Board Member at BMC Biology.

A new regulator of lipid metabolism

orsai is a key player in Drosophila lipid homeostasis, coordinating responses of the fat body to stage-specific demands

Effects of folate on transcriptome methylation

Xie and colleagues identify an influence of folate on mRNA m5C methylation and translation in neural stem cells

Featured Review

Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates

P. Martinez, L. Ballarin, A. V. Ereskovsky, E. Gazave, B. Hobmayer, L. Manni, E. Rottinger, S. G. Sprecher, S. Tiozzo, A. Varela-Coelho and B. Rinkevich

Published 20 Jan 2022


  1. Authors: Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M. Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz…

X-ray computed tomography in life sciences
Shelley D. Rawson et al.
Published 27 February 2020

The merger that made us
Buzz Baum and David Baum
Published 24 June 2020

Protein assembly systems in natural and synthetic biology
Giulio Chiesa et al.
Published: 26 March 2020

Improving the usability and comprehensiveness of microbial databases​​​​​​​
Caitlin Loeffler et al.
Published: 07 April 2020

Focus: Ancient DNA

Latest Papers: Ancient DNA and Human Evolution

Analysis of archaic human haplotypes suggests that 5hmC acts as an epigenetic guide for NCO recombination
Bernett Lee et al.

Published in BMC Biology 4 August 2022

Palaeoecological differences underlie rare co-occurrence of Miocene European primates
Daniel DeMiguel et al.

Published in BMC Biology 19 January 2021

Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences
Cesare de Filippo et al.

Published in BMC Biology 25 October 2021

Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo, Michael J. Dover and David E. MacHugh

Published in BMC Biology 02 December 2019

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Nature Communitites: Behind the Paper

We are now collaborating with Nature Communities, allowing authors to share experiences designing the study and collecting data by writing their own blog-style post on the paper. 

Read the latest Behind the Paper articles here:

Cones, sticks and croissants: Early cephalopod evolution
Alexander Pohle
Published Apr 14 2022

Tentacular team up: Deep partnerships between sea anemones and bacteria
Shana Goffredi
Published Jan 18 2021

Who's a Bonehead? Novel Insights into Evolutionary History from Reptilian Skull Roof Structure
Roy Ebel
Published Nov 30 2020

Digging into the past of olive trees
Toni Gabaldón
Published Oct 26 2020