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Genomic history of the Italian population

Marco Sazzini, Paolo Garagnani and colleagues retraced Italians' genetic history, showing early divergence and distinct adaptive evolution for people living in the north and south of Italy.

Network deficits in Huntington’s disease neuronal models

Jordi Alberch and colleagues examined the neuronal ensemble activity and network topology of Huntington’s disease model cultures, finding distinct network alterations in striatal and cortical neurons.

Whole-genome duplications and the evolution of hexapods

A comprehensive analysis of hexapod genomes by Dick Roelofs and colleagues finds limited evidence that WGD plays a significant role in the evolution of hexapods.

The genome of a polar dinoflagellate

Genome assemblies of the polar dinoflagellate Polarella glacialis isolated from the Arctic and Antarctica, by Cheong Xin Chan and colleagues shed light on the evolution of dinoflagellates, and the genomic adaptation to extreme cold.

Hybrid origin of Candida albicans

New research from Verónica Mixão and Toni Gabaldón provides genomic evidence that Candida albicans strains derive from a single hybrid ancestor, and diverged by loss of heterozygosity.

Call for papers: Research Synthesis and Meta-research in Biology

We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.

Featured Editorial

Introducing our series: research synthesis and meta-research in biology

Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod & Wolfgang Viechtbauer

Published 05 March 2020


Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo et al.
Published 02 December 2019

Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops
Vânia C. S. Pankievicz et al.
Published 03 December 2019

The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019

The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019

Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019

  1. Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

    Content type: Research article

Focus: the Neurobiology in health and disease

Read the latest papers on neurobiology across BMC flagship journals.

Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer’s disease
Young Jae Woo et al.

Published in BMC Medicine 06 February 2020

Selective processing of all rotational and translational optic flow directions in the zebrafish pretectum and tectum​​​​​​​
Kun Wang et al.

Published in BMC Biology 29 March 2019

De novo and inherited TCF20 pathogenic variants are associated with intellectual disability, dysmorphic features, hypotonia, and neurological impairments with similarities to Smith–Magenis syndrome​​​​​​​
Francesco Vetrini et al.

Published in Genome Medicine 28 February 2019

Hemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons
Peipei Li et al.
Published in Genome Biology 09 March 2020

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Announcement: COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.