Figure 6

Comparison of the predicted ordering of cellular innovations, and the corresponding molecular machines, under the inside-out and autogenous outside-in models. Ran, Rab, Sar1, and Rho refer to small GTPase subfamilies. Abbreviations: LINC = Linker of Nucleoskeleton and Cytoskeleton; COPII = Coat protein II; SNAREs = SNAP Receptors.