Erratum | Open | Published:
Erratum to: Type IV collagen drives alveolar epithelial–endothelial association and the morphogenetic movements of septation
BMC Biologyvolume 14, Article number: 73 (2016)
The original article was published in BMC Biology 2016 14:59
Unfortunately, the original version of this article  contained errors. Figure 1 was included incorrectly. The corrected Fig. 1 has been corrected in the original article and Fig. 1 is included correctly below.
Additionally there are minor typographical errors stated below:
Page 4, second paragraph, third sentence: "week" should be "weak", and the figure panel mentioned last in that sentence should read, "(Fig. 1i-k), not g-i.
The correct sentence is below:
"Col4a1mRNA expression was very weak at epithelial tips and surrounding mesenchyme at E16.5 (Fig. 1 h), but later, at E18.5, P6, and P30, it was clearly found in the lung interstitium and at the tips of the developing septa (Fig. 1 i-k)."
Page 8, first paragraph, first sentence contains a split infinitive; it should read, "To show abnormalities more clearly in the development of type I pneumonocytes…".
Page 11, third paragraph, the word "defects" is missing, which alters the nuance, making this sentence confusing. The sentence should read: "The absence of branching defects may be because we analyzed heterozygous mutants in which sufficient levels of native protein…".
Loscertales M, Nicolaou F, Jeanne M, et al. BMC Biol. 2016;14:59. doi:10.1186/s12915-016-0281-2.
The online version of the original article can be found under doi:10.1186/s12915-016-0281-2.
(A–D) Histology of R26-Cre ER ; Col4a1 +/Flex41 and Tie2-Cre; Col4a1 +/Flex41 mutants, and (E–I) immunohistochemistry analysis of PDPL-pSPC, HOPX, α-SMA, tropoelastin, and elastin in R26-Cre ER ; Col4a1 +/Flex41. (A, B) Hematoxylin and eosin shows that both R26-Cre ER ; Col4a1 +/Flex41 and Tie2-Cre; Col4a1 +/Flex41 mutants have simplified alveolarization. (C) R26-Cre ER ; Col4a1 +/Flex41 septa are thick and with numerous blood capillaries (arrowheads) and cells with lipid content (arrows). (D) Tie2-Cre; Col4a1 +/Flex41 septa are small and short with increases in blood capillaries (arrowheads), but not in cells with lipid content. (E) pSPC and PDPL co-staining shows a disorganized alveolar epithelium. (F) R26-Cre ER ; Col4a1 +/Flex41 display a decrease of type I pneumocytes as shown by nuclear staining of HOPX. (G–I) Abnormal localization of α-SMA, tropoelastin and elastin in the septa of R26-Cre ER ; Col4a1 +/Flex41 lungs. Scale bars = 200 μm in A and B, 35 μm in C and D, 50 μm in E, and 100 μm in F to I. (TIF 24706 kb)