Fig. 2
From: Multi-omic profiling of pituitary thyrotropic cells and progenitors
Epigenomic marks and expression for three key transcription factors. a Isl1 encodes a key pituitary transcription factor that is expressed in both TαT1 (red) and GHF-T1 (blue) cell lines. Data from RNA-Seq, CUT&RUN for active chromatin marks (H3K27Ac and H3K4Me1), open chromatin (ATAC-seq), and CUT&RUN for repressive chromatin marks (H3K27Me3) is visualized for each cell line in genome browser tracks. b Gli3 is in active chromatin and expressed in GHF-T1 cells. Gli3 is not expressed in TαT1 cells, and the chromatin is inaccessible with repressive marks. c Rxrg is expressed and in active chromatin in TαT1 cells, while not expressed and bearing repressive marks in GHF-T1 cells. N = 2 for histone marks/cell line