Fig. 2From: Adipoclast: a multinucleated fat-eating macrophageThe transition from obese to severely obese state is characterized by increased macrophage infiltration and the formation of TREM2 and CD9 expressing pro-inflammatory macrophages that eventually give rise to multinucleated adipoclasts surrounding stressed adipocytes. How fusion/multinucleation affects the expression TREM2/CD9 and whether this causes de novo expression of adipoclasts markers is yet to be determinedBack to article page