Fig. 4

Collecting duct and nephron progenitors share a minor pool of genes whose expression is regulated by MAPK/ERK in both tissues. A Heatmap analysis of 362 shared genes in UB and MM. Twelve inversely expressed genes are shown in the middle of the heatmap. B Gene Ontology (GO) biological process analysis of shared genes between UB and MM. C GO molecular function analysis of shared genes between UB and MM. D GO biological process analysis of downregulated shared genes. E GO molecular function analysis of downregulated shared genes. Blue bars represent input DEGs from our RNA-Seq, and red bars represent genes in annotation. Abbreviations: ncRNA; non-coding ribonucleic acid, NT; nucleotide, RNP; ribonucleoprotein, RNT; ribonucleotide.  Detailed lists of all biological processes and the genes that make them up are provided in Additional file 6: Table S5