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  1. The aim of study was to observe the effect of increased lactate levels during high-intensity interval training (HIIT) on protein lactylation, identify the target protein, and investigate the regulatory effect ...

    Authors: Xuefei Chen, Wenhua Huang, Jingbo Zhang, Yanjun Li, Zheng Xing, Lanlan Guo, Hongfeng Jiang and Jing Zhang
    Citation: BMC Biology 2023 21:196
  2. Adelphocoris suturalis (Hemiptera: Miridae) is a notorious agricultural pest, which causes serious economic losses to a diverse range of agricultural crops around the world. The poor understanding of its genomic ...

    Authors: Zhongping Xu, Guanying Wang, Jing Luo, Mingju Zhu, Lisong Hu, Sijia Liang, Bo Li, Xingxing Huang, Ying Wang, Guangyu Zhang, Can Zhang, Yi Zhou, Daojun Yuan, Taiyu Chen, Lizhen Chen, Weihua Ma…
    Citation: BMC Biology 2023 21:195
  3. Worldwide invasion and expansion of Aedes albopictus, an important vector of dengue, chikungunya, and Zika viruses, has become a serious concern in global public health. Chemical insecticides are the primary mean...

    Authors: Yijia Guo, Ke Hu, Jingni Zhou, Zhensheng Xie, Yijie Zhao, Siyu Zhao, Jinbao Gu, Xiaohong Zhou, Guiyun Yan, Anthony A. James and Xiao-Guang Chen
    Citation: BMC Biology 2023 21:194
  4. Prefoldin is an evolutionarily conserved co-chaperone of the tailless complex polypeptide 1 ring complex (TRiC)/chaperonin containing tailless complex 1 (CCT). The prefoldin complex consists of six subunits th...

    Authors: Ismail Tahmaz, Somayeh Shahmoradi Ghahe, Monika Stasiak, Kamila P. Liput, Katarzyna Jonak and Ulrike Topf
    Citation: BMC Biology 2023 21:193
  5. Lauraceae is well known for its significant phylogenetic position as well as important economic and ornamental value; however, most evergreen species in Lauraceae are restricted to tropical regions. In contras...

    Authors: Danqing Li, Han-Yang Lin, Xiuyun Wang, Bo Bi, Yuan Gao, Lingmei Shao, Runlong Zhang, Yuwei Liang, Yiping Xia, Yun-Peng Zhao, Xiaofan Zhou and Liangsheng Zhang
    Citation: BMC Biology 2023 21:192
  6. Trypanosomatids are parasitic flagellates well known because of some representatives infecting humans, domestic animals, and cultural plants. Many trypanosomatid species bear RNA viruses, which, in the case of...

    Authors: Diego H. Macedo, Danyil Grybchuk, Jana Režnarová, Jan Votýpka, Donnamae Klocek, Tatiana Yurchenko, Jan Ševčík, Alice Magri, Michaela Urda Dolinská, Kristína Záhonová, Julius Lukeš, Elena Servienė, Alexandra Jászayová, Saulius Serva, Marina N. Malysheva, Alexander O. Frolov…
    Citation: BMC Biology 2023 21:191
  7. Labeling efficiency is a crucial parameter in fluorescence applications, especially when studying biomolecular interactions. Current approaches for estimating the yield of fluorescent labeling have critical dr...

    Authors: Chiara Schirripa Spagnolo, Aldo Moscardini, Rosy Amodeo, Fabio Beltram and Stefano Luin
    Citation: BMC Biology 2023 21:190
  8. Researchers performing high-quality systematic reviews search across multiple databases to identify relevant evidence. However, the same publication is often retrieved from several databases. Identifying and r...

    Authors: Kaitlyn Hair, Zsanett Bahor, Malcolm Macleod, Jing Liao and Emily S. Sena
    Citation: BMC Biology 2023 21:189
  9. Intrinsically disordered regions (IDRs) are widely distributed in proteins and related to many important biological functions. Accurately identifying IDRs is of great significance for protein structure and fun...

    Authors: Yi-Jun Tang, Ke Yan, Xingyi Zhang, Ye Tian and Bin Liu
    Citation: BMC Biology 2023 21:188
  10. The continuously developing pesticide resistance is a great threat to agriculture and human health. Understanding the mechanisms of insecticide resistance is a key step in dealing with the phenomenon. Insect c...

    Authors: Li-Wei Meng, Guo-Rui Yuan, Meng-Ling Chen, Li-Sha Zheng, Wei Dou, Yu Peng, Wen-Jie Bai, Zhen-Yu Li, John Vontas and Jin-Jun Wang
    Citation: BMC Biology 2023 21:187
  11. Studies have shown that paternal stress prior to conception can influence the innate behaviours of their offspring. The evolutionary impacts of such intergenerational effects are therefore of considerable inte...

    Authors: Lucas B. Hoffmann, Evangeline A. McVicar, Rebekah V. Harris, Coralina Collar-Fernández, Michael B. Clark, Anthony J. Hannan and Terence Y. Pang
    Citation: BMC Biology 2023 21:186
  12. Understanding how spatial patterns of gene expression emerge from the interaction of individual gene networks is a fundamental challenge in biology. Developing a synthetic experimental system with a common the...

    Authors: Kevin Simpson, Alfredo L’Homme, Juan Keymer and Fernán Federici
    Citation: BMC Biology 2023 21:185
  13. Monogenetic inborn errors of metabolism cause a wide phenotypic heterogeneity that may even differ between family members carrying the same genetic variant. Computational modelling of metabolic networks may id...

    Authors: Christoff Odendaal, Emmalie A. Jager, Anne-Claire M. F. Martines, Marcel A. Vieira-Lara, Nicolette C. A. Huijkman, Ligia A. Kiyuna, Albert Gerding, Justina C. Wolters, Rebecca Heiner-Fokkema, Karen van Eunen, Terry G. J. Derks and Barbara M. Bakker
    Citation: BMC Biology 2023 21:184
  14. In contrast to modern rational metabolic engineering, classical strain development strongly relies on random mutagenesis and screening for the desired production phenotype. Nowadays, with the availability of b...

    Authors: Philipp T. Baumann, Michael Dal Molin, Hannah Aring, Karin Krumbach, Moritz-Fabian Müller, Bas Vroling, Philana V. van Summeren-Wesenhagen, Stephan Noack and Jan Marienhagen
    Citation: BMC Biology 2023 21:183
  15. Environmental conditions vary among deserts across the world, spanning from hyper-arid to high-elevation deserts. However, prior genomic studies on desert adaptation have focused on desert and non-desert compa...

    Authors: Xingwen Peng, Jilong Cheng, Hong Li, Anderson Feijó, Lin Xia, Deyan Ge, Zhixin Wen and Qisen Yang
    Citation: BMC Biology 2023 21:182
  16. Functional role of Rho GDP-dissociation inhibitor beta (RhoGDIβ) in tumor biology appears to be contradictory across various studies. Thus, the exploration of the molecular mechanisms underlying the differenti...

    Authors: Xiaohui Hua, Ronghao Zou, Xiaoyue Bai, Yuyao Yang, Juan Lu and Chuanshu Huang
    Citation: BMC Biology 2023 21:181
  17. Cleaning symbioses are captivating interspecific interactions in which a cleaner fish removes ectoparasites from its client, contributing to the health and diversity of natural fish communities and aquaculture...

    Authors: Jingliang Kang, Sandra Ramirez-Calero, José Ricardo Paula, Yifang Chen and Celia Schunter
    Citation: BMC Biology 2023 21:180
  18. The radiation of mammals at the extinction of the dinosaurs produced a plethora of new forms—as diverse as bats, dolphins, and elephants—in only 10–20 million years. Behind the scenes, adaptation to new niches...

    Authors: Margarita V. Brovkina, Margaret A. Chapman, Matthew L. Holding and E. Josephine Clowney
    Citation: BMC Biology 2023 21:179
  19. Health outcomes among children born prematurely are known to be sexually dimorphic, with male infants often more affected, yet the mechanism behind this observation is not clear. CpG methylation levels in the ...

    Authors: Hudson P. Santos Jr., Adam E. Enggasser, Jeliyah Clark, Kyle Roell, Vasyl Zhabotynsky, William Adam Gower, Diana Yanni, Nou Gao Yang, Lisa Washburn, Semsa Gogcu, Carmen J. Marsit, Karl Kuban, T. Michael O’Shea and Rebecca C. Fry
    Citation: BMC Biology 2023 21:173
  20. Lotus corniculatus is a widely distributed perennial legume whose great adaptability to different environments and resistance to barrenness make it an excellent forage and ecological restoration plant. However, i...

    Authors: Cheng Chen, Kaixuan Zhang, Fu Liu, Xia Wang, Yang Yao, Xiaolei Niu, Yuqi He, Jun Hong, Fang Liu, Qiu Gao, Yi Zhang, Yurong Li, Meijuan Wang, Jizhen Lin, Yu Fan, Kui Ren…
    Citation: BMC Biology 2023 21:176
  21. Cip1-interacting zinc finger protein 1 (CIZ1) forms RNA-dependent protein assemblies that stabilise epigenetic state, notable at the inactive X chromosome in females. CIZ1 has been linked with a range of human...

    Authors: Olivia G. Dobbs, Rosemary H. C. Wilson, Katherine Newling, Justin F.-X. Ainscough and Dawn Coverley
    Citation: BMC Biology 2023 21:175
  22. The maintenance of genome stability in primordial germ cells (PGCs) is crucial for the faithful transmission of genetic information and the establishment of reproductive reserve. Numerous studies in recent dec...

    Authors: Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin and Zi-Jiang Chen
    Citation: BMC Biology 2023 21:174
  23. Behavior consists of the interaction between an organism and its environment, and is controlled by the brain. Brain activity varies at sub-second time scales, but behavioral measures are usually coarse (often ...

    Authors: Maciej M. Jankowski, Ana Polterovich, Alex Kazakov, Johannes Niediek and Israel Nelken
    Citation: BMC Biology 2023 21:172
  24. Working memory capacity impairment is an early sign of Alzheimer's disease, but the underlying mechanisms remain unclear. Clarifying how working memory capacity is affected will help us better understand the p...

    Authors: Li-Xin Jiang, Geng-Di Huang, Yong-Lu Tian, Ri-Xu Cong, Xue Meng, Hua-Li Wang, Chen Zhang and Xin Yu
    Citation: BMC Biology 2023 21:171
  25. The nutrient-absorbing villi of small intestines are renewed and repaired by intestinal stem cells (ISCs), which reside in a well-organized crypt structure. Genetic studies have shown that Wnt molecules secret...

    Authors: Jinnan Xiang, Jigang Guo, Shaoyang Zhang, Hongguang Wu, Ye-Guang Chen, Junping Wang, Baojie Li and Huijuan Liu
    Citation: BMC Biology 2023 21:169
  26. Autopolyploidy is a valuable model for studying whole-genome duplication (WGD) without hybridization, yet little is known about the genomic structural and functional changes that occur in autopolyploids after ...

    Authors: Rui-Min Yu, Ning Zhang, Bo-Wen Zhang, Yu Liang, Xiao-Xu Pang, Lei Cao, Yi-Dan Chen, Wei-Ping Zhang, Yang Yang, Da-Yong Zhang, Er-Li Pang and Wei-Ning Bai
    Citation: BMC Biology 2023 21:168
  27. The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in pluripotent and cancer cells, but otherwise dispensable for most mammalian ce...

    Authors: David C. Klein, Santana M. Lardo, Kurtis N. McCannell and Sarah J. Hainer
    Citation: BMC Biology 2023 21:167
  28. The extracellular space between the cell wall and plasma membrane is a battlefield in plant-pathogen interactions. Within this space, the pathogen employs its secretome to attack the host in a variety of ways,...

    Authors: Ran Li, Xi-Yue Ma, Ye-Jing Zhang, Yong-Jun Zhang, He Zhu, Sheng-Nan Shao, Dan-Dan Zhang, Steven J. Klosterman, Xiao-Feng Dai, Krishna V. Subbarao and Jie-Yin Chen
    Citation: BMC Biology 2023 21:166
  29. The development of cotton fiber is regulated by the orchestrated binding of regulatory proteins to cis-regulatory elements associated with developmental genes. The cis–trans regulatory dynamics occurred throughou...

    Authors: Yu Bao, Yangyang Wei, Yuling Liu, Jingjing Gao, Shuang Cheng, Guanqing Liu, Qi You, Peng Liu, Quanwei Lu, Pengtao Li, Shulin Zhang, Nan Hu, Yangshuo Han, Shuo Liu, Yuechao Wu, Qingqing Yang…
    Citation: BMC Biology 2023 21:165
  30. Individual functional modifications shape the ability of wildlife populations to cope with anthropogenic environmental changes. But instead of adaptive response, human-altered environments can generate a succe...

    Authors: Clément Car, André Gilles, Elen Goujon, Marie-Laure Delignette Muller, Luc Camoin, Sandrine Frelon, Pablo Burraco, Samuel Granjeaud, Emilie Baudelet, Stéphane Audebert, Germán Orizaola, Jean Armengaud, Arthur Tenenhaus, Imène Garali, Jean-Marc Bonzom and Olivier Armant
    Citation: BMC Biology 2023 21:164
  31. Smell abilities differ greatly among vertebrate species due to distinct sensory needs, with exceptional variability reported in the number of olfactory genes and the size of the odour-processing regions of the...

    Authors: Demian Burguera, Francesco Dionigi, Kristina Kverková, Sylke Winkler, Thomas Brown, Martin Pippel, Yicheng Zhang, Maxwell Shafer, Annika L. A. Nichols, Eugene Myers, Pavel Němec and Zuzana Musilova
    Citation: BMC Biology 2023 21:163
  32. Deceptive alternative mating tactics are commonly maintained at low frequencies within populations because males using them are less competitive and acquire lower fitness than those using dominant tactics. How...

    Authors: Maria J. Albo, Camila Pavón-Peláez, Mauro Martínez Villar, Bruno A. Buzatto and Ivanna Tomasco
    Citation: BMC Biology 2023 21:162
  33. Pennisetum giganteum (AABB, 2n = 4x = 28) is a C4 plant in the genus Pennisetum with origin in Africa but currently also grown in Asia and America. It is a crucial forage and potential energy grass with significa...

    Authors: Longsheng Xing, Meijia Wang, Qiang He, Hongyu Zhang, Hanfei Liang, Qinghong Zhou, Yu Liu, Ze Liu, Yu Wang, Cailian Du, Yao Xiao, Jianan Liu, Wei Li, Guixia Liu and Huilong Du
    Citation: BMC Biology 2023 21:161
  34. Conversion or editing of adenosine (A) into inosine (I) catalyzed by specialized cellular enzymes represents one of the most common post-transcriptional RNA modifications with emerging connection to disease. A...

    Authors: Fang Wang, Huifen Cao, Qiu Xia, Ziheng Liu, Ming Wang, Fan Gao, Dongyang Xu, Bolin Deng, Yong Diao and Philipp Kapranov
    Citation: BMC Biology 2023 21:160
  35. Neurotransmitter release depends on the fusion of synaptic vesicles with the presynaptic membrane and is mainly mediated by SNARE complex assembly. During the transition of Munc18-1/Syntaxin-1 to the SNARE com...

    Authors: Xianping Wang, Jihong Gong, Le Zhu, Huidan Chen, Ziqi Jin, Xiaoqiang Mo, Shen Wang, Xiaofei Yang and Cong Ma
    Citation: BMC Biology 2023 21:158
  36. Aphids are common crop pests. These insects reproduce by facultative parthenogenesis involving several rounds of clonal reproduction interspersed with an occasional sexual cycle. Furthermore, clonal aphids giv...

    Authors: Thomas C. Mathers, Roland H. M. Wouters, Sam T. Mugford, Roberto Biello, Cock van Oosterhout and Saskia A. Hogenhout
    Citation: BMC Biology 2023 21:157
  37. Prime editing (PE) is the most recent gene editing technology able to introduce targeted alterations to the genome, including single base pair changes, small insertions, and deletions. Several improvements to ...

    Authors: N. Dirkx, Wout J. Weuring, E. De Vriendt, N. Smal, J. van de Vondervoort, Ruben van ’t Slot, M. Koetsier, N. Zonnekein, Tim De Pooter, S. Weckhuysen and B. P. C. Koeleman
    Citation: BMC Biology 2023 21:156
  38. Adenine base editors (ABEs) are promising therapeutic gene editing tools that can efficiently convert targeted A•T to G•C base pairs in the genome. However, the large size of commonly used ABEs based on SpCas9...

    Authors: Yuqiang Qian, Di Wang, Wenchao Niu, Ding Zhao, Jinze Li, Zhiquan Liu, Xun Gao, Yang Han, Liangxue Lai and Zhanjun Li
    Citation: BMC Biology 2023 21:155
  39. The standard evolutionary theory of ageing proposes that ageing occurs because of a trade-off between reproduction and longevity. Eusocial insect queens exhibit positive fecundity-longevity associations and so...

    Authors: David H. Collins, David C. Prince, Jenny L. Donelan, Tracey Chapman and Andrew F. G. Bourke
    Citation: BMC Biology 2023 21:153
  40. Rodents utilize chemical cues to recognize and avoid other conspecifics infected with pathogens. Infection with pathogens and acute inflammation alter the repertoire and signature of olfactory stimuli emitted ...

    Authors: Jan Weiss, Hélène Vacher, Anne-Charlotte Trouillet, Trese Leinders-Zufall, Frank Zufall and Pablo Chamero
    Citation: BMC Biology 2023 21:152
  41. Chronic kidney disease (CKD) accelerates atherosclerosis, but the mechanisms remain unclear. Tyrosine sulfation has been recognized as a key post-translational modification (PTM) in regulation of various cellu...

    Authors: Daopeng Dai, Zhengbin Zhu, Hui Han, Tian Xu, Shuo Feng, Wenli Zhang, Fenghua Ding, Ruiyan Zhang and Jinzhou Zhu
    Citation: BMC Biology 2023 21:151
  42. Biological aging is an important factor leading to the development of pathologies associated with metabolic dysregulation, including type 2 diabetes, cancer, cardiovascular and neurodegenerative diseases. Telo...

    Authors: Xue Liu, Ahmed Elagamy Mohamed Mahmoud Khalil, Uthayakumar Muthukumarasamy, Yasuhiro Onogi, Xiaocheng Yan, Inderjeet Singh, Elena Lopez-Gonzales, Andreas Israel, Alberto Cebrian Serrano, Till Strowig and Siegfried Ussar
    Citation: BMC Biology 2023 21:150
  43. Some dendrobatid poison frogs sequester the toxin epibatidine as a defense against predators. We previously identified an amino acid substitution (S108C) at a highly conserved site in a nicotinic acetylcholine...

    Authors: Julia M. York, Cecilia M. Borghese, Andrew A. George, David C. Cannatella and Harold H. Zakon
    Citation: BMC Biology 2023 21:144
  44. Epigenetic processes are proposed to be a mechanism regulating gene expression during phenotypic plasticity. However, environmentally induced changes in DNA methylation exhibit little-to-no association with di...

    Authors: Samuel N. Bogan, Marie E. Strader and Gretchen E. Hofmann
    Citation: BMC Biology 2023 21:149
  45. Unidirectional regeneration in the basal chordate Ciona intestinalis involves the proliferation of adult stem cells residing in the branchial sac vasculature and the migration of progenitor cells to the site of d...

    Authors: William R. Jeffery, Bo Li, Mandy Ng, Lianwei Li, Špela Gorički and Li Ma
    Citation: BMC Biology 2023 21:148
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